Genetic Connections to Breast Cancer.
The first genes identified to be linked to breast cancer are BRCA1 and BRCA2. Mutated forms of these genes are believed to be responsible for about half the cases of inherited breast cancer. They are especially linked to cancer within younger women. Both of these genes operate to suppress tumours.
BRCA2 is found on the Chromosome 13 and is involved in the repair of DNA strands.
BRCA1 mutations. These are known to increase the risk of breast cancer to 71% by the age of 70, and of breast and ovarian cancer to 83% by the age of 70.(ref. Pr. A Macdonald, Herriot Watt University)
Further information can be found within the at
National Human Genome Research Institute Website
additional links within that site to related information are
tumour suppresser gene
This is a page from
www.genefaith.org created by A. J. Palmer.
This page was updated on 2nd December 2002